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Pipeline / Complete Pipeline
- Centralized Ex-Vivo Lung Evaluation System (EVLP)
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Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Devices / Pivotal TrialEx-vivo lung perfusion (EVLP) is a process used to measure lung function prior to transplant.
LEARN MORE Close - RemoPro™ (treprostinil prodrug)
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Product
RemoPro™
(treprostinil prodrug)Therapeutic Platform
Remodulin®Targeted Indication
Pulmonary Hypertension (PH) WHO Group 1 (PAH)Status
Phase 1Prodrug of treprostinil that is being developed to reduce site pain associated with subcutaneous delivery of treprostinil.
LEARN MORE Close - TETON Studies (inhaled treprostinil)
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Therapeutic Platform
Tyvaso®Targeted Indication
Idiopathic Pulmonary Fibrosis (IPF)Status
Phase 3Randomized, Double-Blind, Placebo-Controlled, Phase 3 Studies of the Efficacy and Safety of Inhaled Treprostinil in Patients with Idiopathic Pulmonary Fibrosis (IPF).
LEARN MORE Close - ADVANCE Study Ralinepag (IP receptor agonist)
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Therapeutic Platform
NCE / Novel BiologicsTargeted Indication
Pulmonary Hypertension (PH) WHO Group 1 (PAH)Status
Phase 3An IP receptor agonist that is a next-generation, once-a-day oral therapy that targets the prostacyclin pathway for patients with pulmonary arterial hypertension (PAH).
LEARN MORE Close - UKidney™ (xenokidney)
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Product
UKidney™
(xenokidney)Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Pre-clinical - UThymoKidney™ (xenokidney)
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Product
UThymoKidney™
(xenokidney)Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Pre-clinical - UHeart™ (xenoheart)
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Product
UHeart™
(xenoheart)Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Pre-clinical - Genetically-Enhanced Mesenchymal stem cells (GEM)
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Therapeutic Platform
NCE / Novel BiologicsTargeted Indication
SepsisStatus
Phase 1 - ULobe™ (Lung Lobes)
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Product
ULobe™
(Lung Lobes)Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Pre-clinicalULobe™ is a decellularized porcine lung scaffold that have been recellularized with human allogeneic lung cells.
LEARN MORE Close - ULung™ (3DAP Lungs)
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Product
ULung™
(3DAP Lungs)Therapeutic Platform
Organ ManufacturingTargeted Indication
End-stage Organ DiseaseStatus
Pre-clinicalULung™ is a 3D printed lung scaffold that is cellularized with either allogeneic cells or a patient's own cells.
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